Bioconjugate Chemistry published the study, “Characterization and Biodistribution Analysis of Oxygen-Doped Single-Walled Carbon Nanotubes Used as in Vivo Fluorescence Imaging Probes” Mar. 8, 2019, to the web. According to Tsukasa Takeuchi, et al., Single-walled carbon nanotubes (SWCNTs) show promise for angiographic imaging. Specifically, oxygen-doped SWCNTs emit fluorescence at roughly 1300 nm when excited with 980-nm light.
In this animal test, researchers found that mice injected with these particles displayed fluorescence in the liver and spleen up to 1 month after injection. The researchers also found no evidence of high toxicity. These factors together make oxygen-doped-SWCNTs a promising option for imaging.
In the course of their research, Takeuchi, et al., used the CPS Disc Centrifuge for particle characterization. In the field of biomedical research, precision is essential. The CPS Disc Centrifuge completely separates narrow peaks that differ by as little as 3%, and typical precision of reported sizes with internal standard is better than ± 0.25%.
Around the world, researchers and inventors rely on CPS Instruments when accuracy matters most. The CPS disc centrifuge provides a higher resolution than light scattering or particle counting methods at a much faster rate of analysis than competitive sedimentation-based particle sizing instruments. Whether replacing an aging system or increasing capacity with a new system, an investment in a CPS disc centrifuge is an investment in consumer confidence.
View more medical and biopharmaceutical research completed with the Disc Centrifuge here.